Common mistakes causing eye strain with LED accent lighting include over-saturation of RGB colors, lack of a warm ambient baseline light, poor color rendering index (CRI) in LEDs, and flicker-prone bulbs. Using intense magenta or cobalt throughout a room can flatten visual detail and lead to headaches. Skipping dimmers results in harsh brightness levels. To avoid these issues, use warm two thousand seven hundred to three thousand kelvin ambient lighting, high-CRI flicker-free LEDs, and dimmable layers of accent lighting, which create a comfortable and visually accurate environment.